Akash Mourya | Health and Medicine Advances | Best Researcher Award

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Mr. Akash Mourya | Health and Medicine Advances | Best Researcher Award

PhD Scholar | National Institutes of Pharmaceutical Education and Research | India

Mr. Akash Mourya is a promising young pharmacologist specializing in pharmacology and toxicology, with a strong research focus on liver pathophysiology, hepatoprotective drug discovery, and molecular mechanisms underlying hepatic and pulmonary disorders. His ongoing Ph.D. work at NIPER Mohali builds on extensive preclinical and translational research conducted at the Institute of Liver and Biliary Sciences (ILBS), New Delhi, where he has developed expertise in animal models of liver diseases, hemodynamic studies, and hepatic cell culture systems. His research contributions have advanced understanding of non-alcoholic and alcoholic fatty liver diseases, hepatopulmonary and porto-pulmonary hypertension, and liver regeneration mechanisms. He has co-authored seven peer-reviewed publications in high-impact journals, including Journal of Hepatology, JHEP Reports, American Journal of Physiology–Gastrointestinal and Liver Physiology, npj Gut and Liver, ACS Omega, and Life Sciences. His work has collectively received 31 citations, 7 Documents, with an h-index of 3, reflecting growing recognition within the biomedical research community. In addition to journal articles, Mr. Akash Mourya has contributed two book chapters published by Springer Nature (2024) and Academic Press (2025), covering topics such as oxidative stress and pharmacological interventions in liver disease, and PPARγ signaling in diabetes. His research abstracts have been presented at prestigious international conferences, including the American Association for the Study of Liver Diseases (AASLD) and the European Association for the Study of the Liver (EASL). His work integrates pharmacological innovation, molecular biology, and experimental therapeutics, with emphasis on Ayurvedic formulations, CB2 receptor agonists, and novel siRNA nanoparticle delivery systems. Mr. Akash Mourya’s ongoing efforts contribute to translational R&D for liver protection and regeneration, aligning with India’s growing emphasis on integrative pharmacology and precision medicine.

Profiles: Scopus | Google Scholar | ResearchGate | PubMed 

Featured Publications

1. Baweja, S., Kumari, A., Negi, P., Tomar, A., Tripathi, D. M., Mourya, A. K., Rastogi, A., Subudhi, P. D., Thangariyal, S., Kumar, G., Kumar, J., Sood, A., Vashistha, C., Bihari, C., Maiwall, R., & Sarin, S. K. (2023). Hepatopulmonary syndrome is associated with low sphingosine-1-phosphate levels and can be ameliorated by the functional agonist fingolimod. Journal of Hepatology, 79(1), 167–180.

2. Juneja, P., Rahman, S. N. R., Jakhar, D., Mourya, A. K., Tripathi, D. M., Kaur, I., Tiwari, V., & others. (2023). Recombinant VEGF-C (Cys156Ser) improves mesenteric lymphatic drainage and gut immune surveillance in experimental cirrhosis. JHEP Reports, 5(10), 100816.

3. Biswas, S., Yadav, N., Juneja, P., Mourya, A. K., Kaur, S., Tripathi, D. M., & Chauhan, V. S. (2022). Conformationally restricted dipeptide-based nanoparticles for delivery of siRNA in experimental liver cirrhosis. ACS Omega, 7(41), 36811–36824.

4. Kaur, I., Juneja, P., Tiwari, R., Vasudevan, A., Mourya, A. K., Trauner, M., Sarin, S. K., & Tripathi, D. M. (2024). Secondary bile acids in portal blood contribute to liver regeneration in a rat model of partial hepatectomy. American Journal of Physiology – Gastrointestinal and Liver Physiology, 327(4), G645–G658.

5. Tripathi, D. M., Singh, P., Mourya, A. K., & Kaur, S. (2024). Oxidative medicine and novel pharmacological treatment approaches in liver disease. In Adaptation under stressful environments through biological adjustments and interventions (pp. 311–334). Springer Nature.

 

Jie Wu | Health and Medicine | Best Researcher Award

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Prof. Dr. Jie Wu | Health and Medicine | Best Researcher Award

Professor and Lab Director, Shantou University Medical College, China

Prof. Dr. Jie Wu is a Distinguished Professor and Director of the Laboratory of Brain Function and Disease at Shantou University Medical College, China, and formerly served as Professor and Director of the Neurophysiology Laboratory at the Barrow Neurological Institute (BNI), St. Joseph’s Hospital and Medical Center, USA. He earned his M.D. from Xuzhou Medical College in 1983 and Ph.D. in Neurophysiology from Sun Yat-sen University of Medical Sciences in 1990, followed by postdoctoral fellowships at Tohoku University School of Medicine, Japan (1993–1994), and the University of New Mexico, USA (1994–1997). His research focuses on the physiology and pharmacology of nicotinic acetylcholine receptors (nAChRs), molecular mechanisms of epilepsy, and neurodegenerative disorders related to amyloid beta (Aβ) and receptor dysfunction, as well as ATP-sensitive potassium (KATP) channel regulation. Over three decades, he has led groundbreaking neuroscience research funded by the U.S. National Institutes of Health (NIH), the State of Arizona, and various international foundations, making fundamental discoveries in synaptic receptor signaling and neurodegeneration. His pioneering contributions have led to nearly 200 peer-reviewed publications, five book chapters, and eight patents (four U.S. and four Chinese), providing novel insights into receptor-mediated neurological diseases and translational therapies. Among his many honors, Prof. Dr. Jie Wu has received the China National Natural Science Award and the International HH Rosenfield Rekate Pioneer Award, and was listed among the World’s Top 2% Scientists (2022) and elected as a Fellow of the Royal Society of Arts (FRSA, UK, 2024). He serves as Editor-in-Chief and editorial board member for leading international journals and is active in global neuroscience and biomedical societies. With 161 documents, 5,887 citations and an h-index of 44, Prof. Dr. Jie Wu exemplifies research excellence and leadership, advancing global neuroscience through innovation, collaboration, and mentorship that continues to shape the future of brain science and human health worldwide.

Profile: Scopus | ORCID | Google Scholar | ResearchGate | Sci Profiles | Loop | LONGDOM | LinkedIn 

Featured Publications

1. Zhang, X. X., Gao, M., Liu, Q. R., Bi, G. H., Li, X., Yang, H. J., Gardner, E. L., & Wu, J. (2014). Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. Proceedings of the National Academy of Sciences of the United States of America, 111(46), E5007–E5015.

2. Liu, Q., Huang, Y., Xue, F., Simard, A., DeChon, J., Li, G., Zhang, J., Lucero, L., & Wu, J. (2009). A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. Journal of Neuroscience, 29(4), 918–929.

3. Wang, T. N., Yang, W., Wang, Y., Nagaraj, V. J., Liu, Q., & Wu, J. (2012). Label-free measuring and mapping of binding kinetics of membrane proteins in single living cells. Nature Chemistry, 4(10), 846–853.

4. Chen, D. J., Gao, M., Gao, F. F., Su, Q. X., & Wu, J. (2017). Brain cannabinoid receptor 2: Expression, function and modulation. Acta Pharmacologica Sinica, 38(3), 312–316.

5. Okada, Y. C., Wu, J., & Kyuhou, S. (1997). Genesis of MEG signals in a mammalian CNS structure. Electroencephalography and Clinical Neurophysiology, 103(4), 474–485.

 

Song-Wei Li | Medicine Advances | Best Researcher Award

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Dr. Song-Wei Li | Medicine Advances | Best Researcher Award

Lecturer at School of medicine, Shanghai University, China.

Dr. Song-Wei Li is a lecturer at the School of Medicine, Shanghai University, and a marine natural product chemist specializing in secondary metabolites from marine organisms. He obtained his Ph.D. from Nanjing University of Chinese Medicine in 2021, with part of his training at the Shanghai Institute of Materia Medical under the mentorship of Prof. Yue-Wei Guo. With over 20 publications in internationally recognized journals, Dr. Li contributes significantly to marine chemoecology and drug discovery, exploring structurally unique compounds with biological potential.

Publication Profile

Scopus

Orcid

Educational Details

  • Ph.D. in Marine Natural Product Chemistry, Nanjing University of Chinese Medicine, China (2021)

    • Joint training at Shanghai Institute of Materia Medica, Chinese Academy of Sciences

  • M.Sc. in Pharmaceutical Chemistry, Nanchang University, China (2018)

  • B.Sc. in Pharmacy, Nanchang University, China (2015)

Professional Experience

  • Lecturer, School of Medicine, Shanghai University, China (2023–Present)

  • Postdoctoral Researcher, College of Pharmaceutical Science, Zhejiang University of Technology, China (2021–2023)

  • Research Training, Chinese Academy of Sciences Shanghai Institute of Materia Medica (During Ph.D., under Prof. Yue-Wei Guo)

Research Interest

Dr. Li’s research centers on the discovery, structure elucidation, chemoecology, and bioactivity evaluation of secondary metabolites derived from marine benthic invertebrates—including molluscs, sponges, and coelenterates—as well as marine flora. His studies emphasize marine diterpenoids, polypropionates, and macrocyclic natural products with potential anti-tumoral, anti-inflammatory, and antibacterial activities. He also integrates quantum mechanical-NMR methods for stereochemical analysis and structural determination.

Author Metrics

Number of Peer-Reviewed Journal Articles: 9
Publication Years: 2018–2025
Total Journals Covered: 8 (including top-tier journals in organic chemistry and marine natural products)

Research Focus

  • Marine Natural Products Chemistry: Focus on isolation and structural elucidation of unique diterpenoids and polypropionates from South China Sea marine organisms (soft corals, mollusks, sponges).

  • Synthetic Organic Chemistry: Biomimetic synthesis and rearrangement studies.

  • NMR and Quantum Mechanical Analysis: Stereochemical analysis using computational and spectroscopic methods.

  • Bioactivity-Oriented Isolation: Emphasis on anti-inflammatory, anti-tumoral, and antibacterial compounds.

Top Noted Publication

  1. Title: Cembrane-type diterpenoids from the South China Sea soft coral Sarcophyton mililatensis
    Journal: Acta Pharmaceutica Sinica B, 2018, 8, 944-955
    DOI: 10.1016/j.apsb.2018.06.004
    Authors: Song-Wei Li, Fei Ye, Zheng-Dan Zhu, Hui Huang, Shui-Chun Mao, Yue-Wei Guo
    Abstract: This study describes the isolation and structural characterization of cembrane-type diterpenoids from the soft coral Sarcophyton mililatensis found in the South China Sea. The compounds were analyzed for their potential biological activities, contributing to the understanding of their pharmacological properties.

  2. Title: Complex polypropionates from a South China Sea Photosynthetic Mollusk: Isolation and Biomimetic Synthesis Highlighting Novel Rearrangements
    Journal: Angewandte Chemie International Edition, 2020, 59, 12105-12112
    DOI: 10.1002/anie.202002261
    Authors: Qi-Hao Wu, Song-Wei Li, Heng Xu, Hong Wang, Pei Hu, Hao Zhang, Cheng Luo, Kai-Xian Chen, Bastien Nay, Yue-Wei Guo, Xu-Wen Li
    Abstract: The paper presents complex polypropionate compounds isolated from Placobranchus ocellatus, a photosynthetic mollusk. Biomimetic synthesis strategies were used to replicate the novel chemical rearrangements observed in these compounds. The study also discusses their potential biological activities and future applications.

  3. Title: Quantum Mechanica-NMR-aided configuration and conformation of two Unreported Macrocycles Isolated from the Soft Coral Lobophytum sp.: Energy Calculations versus Coupling Constants
    Journal: Organic Letters, 2020, 22, 4093-4096
    DOI: 10.1021/acs.orglett.0c01121
    Authors: Song-Wei Li, Cristina Cuadrado, Li-Gong Yao, Antonio Hernandez Daranas, Yue-Wei Guo
    Abstract: This paper discusses the structural characterization of two previously unreported macrocycles isolated from Lobophytum sp. using quantum mechanical NMR to determine the configuration and conformation. The study compares energy calculations with experimental coupling constants for structural validation.

  4. Title: Rare new bicyclic cembranoid ethers and a novel trihydroxy prenylated guaiane from the Xisha soft coral Lobophytum sp.
    Journal: Bioorganic Chemistry, 2020, 103, 104223
    DOI: 10.1016/j.bioorg.2020.104223
    Authors: Song-Wei Li, Cristina Cuadrado, Xia-Juan Huan, Li-Gong Yao, Ze-Hong Miao, Antonio Hernandez Daranas, Yue-Wei Guo
    Abstract: The paper reports the discovery of new bicyclic cembranoid ethers and a novel trihydroxy prenylated guaiane from Lobophytum sp. (a species of soft coral). The study provides in-depth structural analysis and evaluates their potential as bioactive compounds with anti-inflammatory properties.

  5. Title: Litosetoenins A-E, Diterpenoids from the soft coral Litophyton setoensis, Backbone-rearranged through Divergent Cyclization Achieved by Epoxide Reactivity Inversion
    Journal: The Journal of Organic Chemistry, 2021, 86, 11771-11781
    DOI: 10.1021/acs.jorgchem.0c03360
    Authors: Song-Wei Li, I. Wayan Mudianta, Cristina Cuadrado, Geng Li, Gede A. Yudasmara, Gede I. Setiabudi, Antonio Hernandez Daranas, Yue-Wei Guo
    Abstract: This study describes the isolation of diterpenoids (Litosetoenins A-E) from Litophyton setoensis and their unique structural features, which involve a divergent cyclization process facilitated by epoxide reactivity inversion. These compounds are analyzed for their chemical properties and potential pharmacological activities.

  6. Title: Ocellatuperoxides A-F, Uncommon Anti-Tumoral γ-Pyrone Peroxides from a Photosynthetic Mollusk Placobranchus ocellatus
    Journal: Marine Drugs, 2022, 20, 590
    DOI: 10.3390/md20090590
    Authors: Song-Wei Li, Qihao Wu, Heng Xu, Li-Gong Yao, Cheng Luo, Hong Wang, Hao Zhang, Xu-Wen Li, Yue-Wei Guo
    Abstract: This paper reports the isolation of Ocellatuperoxides A-F, γ-pyrone peroxides from Placobranchus ocellatus, a photosynthetic mollusk. These compounds exhibit anti-tumoral properties, and the study explores their potential therapeutic applications in cancer treatment.

  7. Title: Ocellatuspyrones A-G, new antibacterial polypropionates from the Chinese mollusk Placobranchus ocellatus
    Journal: Marine Life Science & Technology, 2023, 5, 373-386
    DOI: 10.1007/s42995-023-00042-2
    Authors: Song-Wei Li, Dan-Dan Yu, Ming-Zhi Su, Li-Gong Yao, Hong Wang, Xue-Ting Liu, Yue-Wei Guo
    Abstract: The paper describes the isolation of new antibacterial polypropionates (Ocellatuspyrones A-G) from Placobranchus ocellatus, examining their structure and antibacterial activities, providing insights into their potential use in treating bacterial infections.

  8. Title: Macrocyclic anti-inflammatory diterpenes from the South China Sea soft coral Sinularia erecta and their isolation by combined column chromatography
    Journal: Journal of Chromatography A, 2024, 1736, 465416
    DOI: 10.1016/j.chroma.2024.465416
    Authors: Song-Wei Li, Cristina Cuadrado, Jiao Liu, Heng Li, Wei Tang, Antonio Hernandez Daranas, Yue-Wei Guo
    Abstract: This study focuses on the isolation of macrocyclic anti-inflammatory diterpenes from Sinularia erecta, a soft coral from the South China Sea. Combined column chromatography was employed to isolate these compounds, which were then analyzed for their anti-inflammatory properties.

  9. Title: Uncommon Diterpenoids with Diverse Frameworks from the South China Sea Sponge Spongia officinalis and Their Anti-inflammatory Activities
    Journal: The Journal of Organic Chemistry, 2025, 90: 1950-1956
    DOI: 10.1021/acs.jorgchem.5b00123
    Authors: Song-Wei Li, Jiao Liu, Zi-Yi Liu, Yan Fu, Li-Gong Yao, Yu-Cheng Gu, Hai-Yan Zhang, Xu-Wen Li, Yue-Wei Guo
    Abstract: This research highlights the discovery of uncommon diterpenoids from the South China Sea sponge Spongia officinalis. The paper focuses on their diverse chemical frameworks and anti-inflammatory activities, with a focus on their potential therapeutic applications.

Conclusion

Dr. Song-Wei Li stands out as a highly deserving candidate for the Best Researcher Award due to his innovative research in marine natural products chemistry, his high-impact publications, and his unique interdisciplinary approach. His work has the potential to contribute significantly to drug discovery, particularly in areas of anti-inflammatory, anti-tumoral, and antibacterial therapies. With continued engagement in global scientific networks and an expansion of his research focus, Dr. Li is poised to make even greater contributions to science.