Innovative Research Award
Somdeb Bose Dasgupta
Indian Institute of Technology, Kharagpur, India
Somdeb Bose Dasgupta is a researcher at the Indian Institute of Technology Kharagpur whose work spans molecular immunology, cellular microbiology, host–pathogen interactions, and biomedical research. His publicly documented research includes investigations of infectious-disease mechanisms, molecular targets, cellular signaling, and biologically active compounds. The institutional research profile identifies his laboratory as working on molecular immunology and cellular microbiology, including host factors involved in parasite pathogenesis and mechanisms associated with mycobacterial infection.[1]
Abstract
This academic recognition profile summarizes the research activities and scholarly record of Somdeb Bose Dasgupta at the Indian Institute of Technology Kharagpur. His research is situated primarily within molecular immunology and cellular microbiology, with work addressing infectious diseases, host–pathogen interactions, molecular mechanisms, and potential therapeutic strategies. Institutional and bibliographic records document a sustained publication record and measurable citation impact.[1]
Keywords
Somdeb Bose Dasgupta, Neuroscience, Molecular Immunology, Cellular Microbiology, Host–Pathogen Interactions, Infectious Diseases, Biotechnology, IIT Kharagpur, Research Impact, Innovative Research Award.
Introduction
Research in molecular immunology and cellular microbiology examines interactions between infectious agents and host cells at molecular and cellular levels. At IIT Kharagpur, Dasgupta’s research program has addressed infectious diseases including tuberculosis and visceral leishmaniasis, with emphasis on molecular targets, host factors, parasite survival, and cellular signaling mechanisms.[2]
His publication record also includes research in biomolecular systems and biomedical applications. Recent collaborative studies have investigated self-assembling biomaterials, antimicrobial activity, gene transfection, protein and DNA binding, and cellular responses to bioactive compounds.[3]
Research Profile
The available academic record identifies Somdeb Bose Dasgupta with the Department of Bioscience and Biotechnology at IIT Kharagpur. His institutional profile describes the Molecular Immunology and Cellular Microbiology Laboratory as a research environment focused on host factors governing parasite pathogenesis, signaling by phosphatases and kinases, macrophage responses, mycobacterial virulence factors, and adaptive resistance mechanisms in Leishmania.[1]
- Institution: Indian Institute of Technology Kharagpur
- Research domain supplied for the award profile: Neuroscience
- Scopus Author ID supplied for the profile: 23032977600
- Documents: 37
- Citations: 980
- h-index: 15
- ORCID: 0000-0001-5446-9582
The IIT Kharagpur institutional research record additionally reports a research profile for Dr. Somdeb Bose Dasgupta and identifies expertise in immunology, with publications extending across multiple years.[1]
Research Contributions
Dasgupta’s documented research contributions include studies of molecular mechanisms associated with infectious disease and host-cell responses. His research has addressed Leishmania and mycobacterial systems, including molecular targets involved in pathogen survival and host responses. Such work connects molecular biology, cellular microbiology, immunology, and biomedical investigation.[2]
His collaborative publication record also includes studies of cationic bolaamphiphiles and related biomolecular assemblies. These investigations have examined self-assembly, gene transfection, antimicrobial activity, cytotoxicity, and interactions with biological macromolecules.[3]
More recent work has included investigations of bioactive compounds and cellular mechanisms relevant to inflammation and neurobiological models. A 2026 publication involving Dasgupta examined Shatavarin IV in LPS-treated SH-SY5Y cells and reported investigation of antioxidant and anti-inflammatory effects through the TrkB-BDNF axis.[4]
Publications
Selected publications associated with Somdeb Bose Dasgupta demonstrate the breadth of his collaborative research across molecular biology, microbiology, biomaterials, and biomedical science. The following publications are presented as representative documented works rather than as a complete bibliography.
- Shatavarin IV, a Bioactive Constituent of Asparagus racemosus, Exerts Antioxidant and Anti-Inflammatory Effects in LPS-Treated Cultured SH-SY5Y Cells via TrkB-BDNF Axis. Journal of the American Nutrition Association, 2026. DOI: 10.1080/27697061.2025.2607514.[4]
- Ultrasound-Assisted Polyphenol Hydrogelation: Mechanistic Insights into Self-Assembly, Antioxidant, and Dual Antibacterial Action against Gram-Positive and Gram-Negative Pathogens. ACS Applied Bio Materials, 2026, 9(1), 236–250. DOI: 10.1021/acsabm.5c01818.[5]
- Novel Cationic Bolaamphiphiles for Protein and DNA Binding, Gene Delivery, and Antimicrobial Applications. Chemistry – An Asian Journal, 2025, 20(9), e202401582. DOI: 10.1002/asia.202401582.[6]
- Impact of Linker Groups on Self-Assembly, Gene Transfection, Antibacterial Activity, and In Vitro Cytotoxicity of Cationic Bolaamphiphiles. ACS Applied Bio Materials, 2024, 7(3), 1703–1712. DOI: 10.1021/acsabm.3c01142.[7]
- Self-Assembly, In Vitro Gene Transfection, and Antimicrobial Activity of Biodegradable Cationic Bolaamphiphiles. Langmuir, 2023, 39(29), 10021–10032. DOI: 10.1021/acs.langmuir.3c00885.[8]
Research Impact
The supplied bibliometric profile records 980 citations across 37 documents and an h-index of 15. These indicators provide quantitative measures of scholarly dissemination within the specified academic indexing context. Bibliometric indicators should be interpreted alongside publication quality, disciplinary context, authorship, and the nature of individual research contributions rather than as standalone measures of research quality.[1]
The research record also demonstrates interdisciplinary collaboration. Published studies associated with Dasgupta involve researchers in biotechnology, chemistry, microbiology, molecular biology, and biomedical sciences, illustrating the cross-disciplinary character of contemporary research in host–pathogen biology and biomolecular applications.[3]
Award Suitability
The Innovative Research Award profile considers documented research activity, scholarly publications, research visibility, and measurable academic indicators. Somdeb Bose Dasgupta’s profile contains an established publication record, indexed research outputs, citation activity, and an h-index reported in the supplied academic data. His research spans molecular immunology, cellular microbiology, host–pathogen interactions, biomolecular assemblies, and biomedical applications, providing a broad scholarly basis for consideration within a research recognition context.[1]
The documented publications further show research addressing antimicrobial activity, gene delivery, cellular responses, and bioactive compounds. These works provide concrete examples of research activity relevant to interdisciplinary biomedical science.[5]
Conclusion
Somdeb Bose Dasgupta is an IIT Kharagpur researcher whose documented scholarly activities encompass molecular immunology, cellular microbiology, infectious-disease research, biomolecular systems, and biomedical applications. His publication and citation records provide measurable evidence of sustained academic activity. His research portfolio also demonstrates interdisciplinary collaboration across molecular and biomedical sciences.[1]
External Links
References
- Indian Institute of Technology Kharagpur. (n.d.). Dr Somdeb Bose Dasgupta — Academic and Research Profile. IIT Kharagpur.
https://iitkgp.irins.org/profile/158034
- Indian Institute of Technology Kharagpur. (n.d.). Department of Bioscience and Biotechnology — Somdeb Bose Dasgupta research statement.
https://bt.iitkgp.ac.in/faculty.html
- Mondal, P., Roy, S., Patra, D., Dasgupta, S. B., & Dey, J. (2025). Novel Cationic Bolaamphiphiles for Protein and DNA Binding, Gene Delivery, and Antimicrobial Applications. Chemistry – An Asian Journal, 20(9), e202401582.
DOI: https://doi.org/10.1002/asia.202401582
- Das, D., Sarkar, D., Dasgupta, S. B., Banik, S. P., & Bagchi, D. (2026). Shatavarin IV, a Bioactive Constituent of Asparagus racemosus, Exerts Antioxidant and Anti-Inflammatory Effects in LPS-Treated Cultured SH-SY5Y Cells via TrkB-BDNF Axis. Journal of the American Nutrition Association, 45(5), 441–450.
DOI: https://doi.org/10.1080/27697061.2025.2607514
- Nandi, P. K., Parida, S., Das, D., Dasgupta, S. B., Mishra, S., & Sarkar, N. (2026). Ultrasound-Assisted Polyphenol Hydrogelation: Mechanistic Insights into Self-Assembly, Antioxidant, and Dual Antibacterial Action against Gram-Positive and Gram-Negative Pathogens. ACS Applied Bio Materials, 9(1), 236–250.
DOI: https://doi.org/10.1021/acsabm.5c01818
- ORCID. (n.d.). ORCID record: Somdeb Bose Dasgupta, ORCID 0000-0001-5446-9582.
https://orcid.org/0000-0001-5446-9582
- American Chemical Society. (2024). Impact of Linker Groups on Self-Assembly, Gene Transfection, Antibacterial Activity, and In Vitro Cytotoxicity of Cationic Bolaamphiphiles. ACS Applied Bio Materials, 7(3), 1703–1712.
DOI: https://doi.org/10.1021/acsabm.3c01142
- American Chemical Society. (2023). Self-Assembly, In Vitro Gene Transfection, and Antimicrobial Activity of Biodegradable Cationic Bolaamphiphiles. Langmuir, 39(29), 10021–10032.
DOI: https://doi.org/10.1021/acs.langmuir.3c00885
- Google Scholar. (n.d.). Google Scholar profile associated with Somdeb Bose Dasgupta.
https://scholar.google.com/citations?user=CLI0L0kAAAAJ&hl=en
- New Scientists Awards. (n.d.). New Scientists Awards.
https://newscientists.net/