Dr. Zhiyuan Fang | Dairy Science | Best Researcher Award

Postdoctoral Researcher at Jilin University | China

Dr. Zhiyuan Fang is currently a Postdoctoral Researcher at Jilin University, China, where he is actively involved in veterinary and animal biosciences research, particularly in dairy cattle metabolic disorders. With a solid track record in high-impact publications, Dr. Fang has authored ten scientific articles in peer-reviewed journals such as Autophagy (5-year), Food & Function (5-year), and Journal of Dairy Science (5-year). His research focuses on the pathogenesis of metabolic diseases, notably ketosis and fatty liver in dairy cows, contributing significantly to the identification of diagnostic biomarkers and the development of prevention and treatment strategies. His studies have accumulated 140 citations and demonstrate his impactful contribution to animal health research. Dr. Fang’s work not only furthers the understanding of disease mechanisms but also supports the dairy industry through applied innovations. His meticulous approach to biomarker discovery and therapeutic design places him at the forefront of veterinary metabolic disease research in China. With a growing publication record and national-level research funding, Dr. Fang continues to advance scientific solutions for improving dairy cattle health and productivity.

Publication Profile

Orcid

Education

Dr. Zhiyuan Fang pursued his doctoral and postdoctoral studies at Jilin University, one of China’s leading institutions in veterinary medicine and life sciences. During his academic journey, he focused extensively on animal metabolism, veterinary pathology, and nutritional biochemistry. His advanced training emphasized experimental techniques in cellular and molecular biology, particularly related to liver function, lipid metabolism, and disease diagnostics in ruminants. His dissertation and postdoctoral projects addressed critical challenges in dairy cow health, including metabolic syndromes such as ketosis and fatty liver, both of which significantly impact dairy productivity and farm economics. In addition to coursework, Dr. Fang actively participated in lab-based research, animal trials, and scientific writing, developing a robust foundation in veterinary research methodologies. His educational background has been marked by academic rigor, collaborative learning, and strong mentorship from experts in veterinary sciences. These academic experiences have empowered him to undertake translational research linking fundamental science to field-level applications. Dr. Fang’s comprehensive educational path continues to serve as a cornerstone for his scholarly contributions and scientific leadership in veterinary health research.

Professional Experience

Dr. Zhiyuan Fang currently serves as a Postdoctoral Researcher at Jilin University, where he leads and contributes to multiple projects focused on metabolic diseases in dairy cattle. His professional responsibilities span experimental design, biomarker discovery, pathological evaluation, and publication of peer-reviewed articles. He has played a pivotal role in research initiatives funded by prestigious national bodies, including the National Natural Science Foundation of China and the China Postdoctoral Science Foundation. With practical experience in both laboratory and field settings, Dr. Fang bridges the gap between basic research and applied veterinary solutions. His work involves extensive collaboration with clinicians, dairy farm operators, and academic mentors to ensure that research findings are both scientifically rigorous and industry-relevant. In addition to research, he mentors junior researchers and contributes to the preparation of grant proposals and scientific manuscripts. Through his professional tenure at Jilin University, Dr. Fang has established himself as a key contributor in the field of veterinary metabolic health and continues to expand his impact through interdisciplinary research and innovative solutions to real-world problems in animal health management.

Research Interest

Dr. Zhiyuan Fang’s research interests lie at the intersection of veterinary science, metabolic disease pathology, and translational diagnostics in dairy cattle. Specifically, he is focused on understanding the pathogenesis of ketosis and fatty liver disease, two of the most prevalent metabolic disorders in high-yielding dairy cows. His interests extend to the identification and validation of novel diagnostic biomarkers that can predict disease onset and progression with high accuracy. Dr. Fang is also passionate about developing preventive nutritional supplements and therapeutic interventions that can mitigate metabolic imbalances. His work integrates molecular biology, veterinary pathology, and nutritional biochemistry, employing advanced techniques such as gene expression profiling, biochemical assays, and metabolic modeling. He is also exploring the interaction between gut microbiota and liver function in cows, a promising area that may yield new preventive strategies. Through his multidisciplinary research, Dr. Fang aims to enhance animal welfare, improve dairy production efficiency, and support sustainable livestock farming. His ultimate goal is to translate laboratory discoveries into practical applications that benefit both veterinarians and farmers.

Research Skills

Dr. Zhiyuan Fang possesses a diverse and advanced skill set in experimental veterinary science and metabolic disease research. His expertise includes molecular and cellular techniques such as PCR, Western blotting, ELISA, immunohistochemistry, and histopathological staining—tools essential for studying hepatic and metabolic dysfunctions. He has hands-on experience in the development and validation of diagnostic biomarkers using both biochemical and molecular assays. Dr. Fang is also proficient in designing and executing animal trials, particularly involving dairy cows, where he monitors metabolic parameters, blood biochemistry, and clinical signs related to ketosis and fatty liver. He is skilled in statistical analysis software and data visualization, allowing for high-quality interpretation and presentation of scientific results. In addition to laboratory competencies, Dr. Fang is adept at manuscript preparation and grant writing, with proven success in securing funding from prestigious national agencies. His interdisciplinary abilities—ranging from veterinary pathology to translational product development—make him a valuable asset to both academic and industry-based research projects.

Awards and Honors

Dr. Zhiyuan Fang’s academic excellence and research contributions have been recognized through competitive funding awards, including grants from the National Natural Science Foundation of China (NSFC) and the China Postdoctoral Science Foundation. These prestigious grants—grant numbers 32402959, GZC20230951, and 2024M751094—are awarded to high-potential researchers making significant strides in scientific innovation. These awards highlight Dr. Fang’s commitment to solving critical issues in animal health and his ability to attract national-level support for his work. While he has not yet received formal awards beyond research grants, his publication in Autophagy—a leading journal in cellular biology with a 5-year impact factor of 16.8—stands as a testament to the high quality and scientific impact of his work. His growing citation index and increasing visibility in the veterinary research community also reflect his emerging leadership in metabolic disease research. Dr. Fang is poised to receive further recognitions as his research continues to evolve and influence both scientific and practical fields in dairy cow health.

Author Metrics

• Total Publications Listed: 8

• Total Citations: 174+

• h-index: 6
  (6 publications have ≥6 citations)

• i10-index: 5
  (5 publications have ≥10 citations)

Publications Top Notes

1. Free fatty acids induce bile acids overproduction and oxidative damage of bovine hepatocytes via inhibiting FXR/SHP signaling
Citation: 4
Year: 2024

2. Nuciferine protects bovine hepatocytes against free fatty acid–induced oxidative damage by activating the transcription factor EB/peroxisome proliferator-activated receptor γ coactivator 1 alpha pathway
Citation: 4
Year: 2024

3. Narirutin activates TFEB to protect against acetaminophen-induced liver injury by targeting PPP3/calcineurin
Citation: 39
Year: 2023

4. Low abundance of mitophagy markers is associated with reactive oxygen species overproduction in cows with fatty liver and causes reactive oxygen species overproduction and lipid accumulation in calf hepatocytes
Citation: 17
Year: 2022

5. Targeting IRE1α and PERK in the endoplasmic reticulum stress pathway attenuates fatty acid-induced insulin resistance in bovine hepatocytes
Citation: 16
Year: 2022

6. Nuciferine protects against high-fat diet-induced hepatic steatosis and insulin resistance via activating TFEB-mediated autophagy–lysosomal pathway
Citation: 63
Year: 2022

7. Overactivation of hepatic mechanistic target of rapamycin kinase complex 1 (mTORC1) is associated with low transcriptional activity of transcription factor EB and lysosomal dysfunction in dairy cows with clinical ketosis
Citation: 13
Year: 2022

8. Nuciferine improves high-fat diet-induced obesity via reducing intestinal permeability by increasing autophagy and remodeling the gut microbiota
Citation: 35
Year: 2021

Conclusion

Dr. Zhiyuan Fang exemplifies a dedicated and innovative early-career researcher in the field of veterinary medicine and animal metabolic health. His focused research on ketosis and fatty liver disease in dairy cows addresses some of the most pressing challenges in the dairy industry. With a strong foundation in molecular diagnostics, biomarker identification, and therapeutic product development, Dr. Fang’s work bridges academic research and practical veterinary applications. Supported by prestigious national grants and a growing body of high-impact publications, his scientific contributions have garnered attention in both academic and applied settings. Dr. Fang’s future trajectory holds promise for transformative developments in animal health diagnostics and sustainable dairy farming practices. His commitment to interdisciplinary research, rigorous experimentation, and knowledge dissemination places him in a strong position to emerge as a thought leader in metabolic disease research. In sum, Dr. Fang’s achievements reflect both depth and innovation, and he is well-positioned to contribute significantly to the advancement of veterinary biosciences in China and beyond.